| Sacramento Kings | National Basketball Association | Sacramento | 1945 | ARCO Arena I, ARCO Arena, Golden 1 Center, Municipal Auditorium, Hy-Vee Arena, Omaha Civic Auditorium, Cincinnati Gardens, Edgerton Park Arena, Blue Cross Arena |
| Saetas de Oro | Copa Peru | — | — | — |
| Salerno Basket 92 | — | — | — | — |
| San Antonio Spurs | National Basketball Association | — | 1967 | Alamodome, Kay Bailey Hutchison Convention Center, HemisFair Arena, Fort Worth Convention Center, Frost Bank Center, Moody Coliseum, Lubbock Municipal Coliseum |
| San Diego Football Club | Major League Soccer | San Diego | 18 de maio de 2023 | Snapdragon Stadium |
| San Diego Padres | Major League Baseball | San Diego | 1969 | PETCO Park |
| San Francisco de Asís de Lonya Grande | Copa Peru | — | 1946 | — |
| San Francisco Giants | Major League Baseball | São Francisco | 1883 | Oracle Park |
| San Jose Sharks | — | — | 1991 | Cow Palace, SAP Center |
| San José Earthquakes | Major League Soccer | São José | 1995 | Avaya Stadium, Buck Shaw Stadium |
| San Lorenzo de Almagro de Chiclayo | Copa Peru | — | — | Estádio Elías Aguirre |
| San Martino di Lupari | — | — | — | — |
| San Martín de Porres de Pucallpa | Copa Peru | — | 9 de abril de 1964 | Estadio Aliardo Soria Pérez |
| San Simón de Moquegua | Campeonato Peruano de Futebol | — | 1983 | Estádio 25 de Novembro |
| Santa Marinella Basket | — | — | — | — |
| Santiago Barranco | Copa Peru | — | 20 de setembro de 1929 | — |
| Santos FC (Peru) | Copa Peru | — | — | Estadio José Picasso Peratta |
| Scafati Basket | Liga Italiana de Basquetebol | Scafati | 1969 | PalaMangano |
| Scaligera Basket Verona | Liga Italiana de Basquetebol | Verona | 1951 | PalaOlimpia |
| Seattle Kraken | — | — | 2021 | Climate Pledge Arena |
| Seattle Mariners | Major League Baseball | — | 1977 | Kingdome, T-Mobile Park |
| Seattle Metropolitans | Pacific Coast Hockey League | Seattle | 1915 | — |
| Seattle Seahawks | National Football League | — | 1976 | Kingdome, Husky Stadium, Lumen Field |
| Seattle Sounders Football Club | Major League Soccer | Seattle | 2009 | Lumen Field |
| Seattle SuperSonics | — | Washington | 1967 | Kingdome, Climate Pledge Arena, Tacoma Dome |
| Sebastiani Basket Club Rieti | — | — | — | — |
| Senati FBC | Copa Peru | — | — | Estádio Mariano Melgar |
| Serrato Pacasmayo | Segunda División (Campeonato Peruano de Futebol) | — | 2012 | Estadio Carlos A. Olivares |
| Sheboygan Red Skins | National Basketball Association | Sheboygan | 1938 | Playdium, Sheboygan Municipal Auditorium and Armory |
| Silver Basket Porto Torres | — | Porto Torres | — | — |
| Sisv Viterbo | — | Viterbo | — | — |
| Societa Veroli Basket | — | Frosinone | 1968 | — |
| Società Ginnastica Triestina | — | Trieste | 1930 | — |
| Spider Fabriano | — | — | — | — |
| Sport Boys Association | Torneo Descentralizado | — | 1927 | Estádio Miguel Grau (Callao) |
| Sport Chorrillos | Copa Peru | — | — | Estádio Campeones del 36 |
| Sport Coopsol | Segunda División (Campeonato Peruano de Futebol) | — | 2000 | Estadio Municipal de Chorrillos |
| Sport Dos de Mayo | Copa Peru | — | — | Union Tarma Stadium |
| Sport Huamanga | Copa Peru | — | 2002 | Estádio Ciudad de Cumaná |
| Sport Inca | — | — | 18 de maio de 1908 | Estadio Nacional del Perú (1897) |
| Sport José Gálvez | — | — | 1902 | Estadio Nacional del Perú (1897) |
| Sport Juan Bielovucic | — | — | — | Estadio Nacional del Perú (1897) |
| Sport Pilsen Callao | Copa Peru | — | 1924 | — |
| Sport Sáenz Peña | — | — | 1906 | Estadio Telmo Carbajo |
| Sport Victoria | Copa Peru | — | 1916 | Estadio José Picasso Peratta |
| Sport Águila | Segunda División (Campeonato Peruano de Futebol) | — | 25 de dezembro de 1947 | — |
| Sporting Bellavista | — | — | 1912 | Estadio Nacional del Perú (1897) |
| Sporting Club Gira | — | Bolonha, Ozzano dell'Emilia | 1945 | — |
| Sporting Pizarro | Copa Peru | — | — | Estadio Mariscal Cáceres |
| Sporting Tabaco (1926–1955) | Campeonato Peruano de Futebol | — | 16 de novembro de 1926 | Estádio Nacional do Peru |
| Sportivo Melgar | — | — | 14 de julho de 1925 | Estadio Nacional del Perú (1897) |
| Sportivo Tarapacá Ferrocarril | — | — | 15 de outubro de 1911 | Estádio Nacional do Peru |
| SS Lazio Basket | — | Roma | 1932 | — |
| St. Louis Blues | — | — | 1967 | Enterprise Center |
| St. Louis Cardinals | Major League Baseball | — | 1882 | Busch Stadium |
| St. Louis City Soccer Club | Major League Soccer | St. Louis | 20 de agosto de 2019 | Energizer Park |
| St. Louis Hawks | National Basketball Association | — | — | — |
| Starlight Valmadrera | — | — | — | — |
| Stella Azzurra Roma | — | Roma | 1938 | — |
| Sutor Basket Montegranaro | — | Montegranaro | 1947 | Banca Marche Palace |